smallpox or the cow-pox; that he had inoculated mothers whose
sucking infants had never undergone either of these diseases;
that the effluvia from the inoculated pustules, in either case,
had been inhaled from day to day during the whole progress of
their maturation, and that there was not the least perceptible
effect from these exposures." One woman he inoculated about a week
previous to her accouchement, that her infant might be the more
fully and conveniently exposed to the pustule; but, as in the
former instances, no infection was given, although the child
frequently slept on the arm of its mother with its nostrils and
mouth exposed to the pustule in the fullest state of maturity. In
a word, is it not impossible for the cow-pox, whose ONLY
manifestation appears to consist in the pustules CREATED BY
CONTACT, to produce ITSELF by effluvia?

In the course of a late inoculation I observed an appearance
which it may be proper here to relate. The punctured part on a
boy's arm (who was inoculated with fresh limpid virus) on the
sixth day, instead of shewing a beginning vesicle, which is usual
in the cow-pox at that period, was encrusted over with a rugged,
amber-coloured scab. The scab continued to spread and increase in
thickness for some days, when, at its edges, a vesicated ring
appeared, and the disease went through its ordinary course, the
boy having had soreness in the axilla and some slight
indisposition. With the fluid matter taken from his arm five
persons were inoculated. In one it took no effect. In another it
produced a perfect pustule without any deviation from the common
appearance; but in the other three the progress of the
inflammation was exactly similar to the instance which afforded
the virus for their inoculation; there was a creeping scab of a